Romantic sparks begin to fly when Patrick Jane and supposed psychic Kristina Frye cross paths again during the CBI investigation into the murder of a charismatic head of a non-profit organization that fights human trafficking.
Jane and the CBI team narrowly escape a fiery end when a building explodes while they're investigating a death threat. Meanwhile, sparks fly between Lisbon and billionaire Walter Mashburn when they meet again while on the case.
Patrick Jane accepts the help of a local astrologer, Ellis Mars, to solve the puzzling case of a triple homicide that involves two policemen and the fiancé of an EMT worker.
The CBI pursues two lines of investigation when a Santa is murdered: Patrick Jane goes undercover in an AA group; and Rigsby and Van Pelt question members of an authentic Santa society. Meanwhile, following the demise of a person in custody at the CBI, J.J. LaRoche is brought in to question the team when it appears to be an inside job.
Patrick and the team investigate the murder of a woman with ties to one of the fighters. Meanwhile, LaRoche focuses his investigation on Rigsby, who in turn is forced to ask Cho for a huge favor in order to keep his job.
When Patrick Jane and the CBI must work with a criminal profiler, Dr. Montague, to solve a double murder, it becomes a competition for Jane to prove that his methods are superior.
Pomoću jedinstvenog dara moderni Sherlock Holmes uvijek je korak ispred forenzičkih analiza, napredne kriminalističke tehnologije i svih kolega. Uočavajući najsitnije detalje, igrajući umne igrice i „čitajući" emocije drugih, Jane kriminalcima kompleksnih profila i poremećenih umova postavlja sofisticirane umne zamke te može navesti svjedoke i osumnjičene da mu razotkriju činjenice kojih ni sami nisu svjesni. Šarmantni i karizmatični Jane ima neslavnu prošlost televizijskog vidovnjaka te je stekao negativni publicitet nakon što je razotkriven kao varalica. Iako je priznao kako nema paranormalne, već samo mentalne sposobnosti, jedina koja i dalje sumnja u njega je narednica CBI-a Teresa Lisbon (Robin Tunney). Iako je nepredvidljiv i poznat po zaobilaženju protokola, njegovi kolege, agenti Kendall Cho (Tim Kang) i Wayne Rigsby (Owain Yeoman) te novakinja Grace Van Pelt (Amanda Righetti), dive se njegovom šarmu i učinkovitosti u rješavanju slučajeva. No Jane skriva još jednu mračnu tajnu iz svoje prošlosti. Naime, nekoliko godina prije početka same radnje Jane je izgubio suprugu i kćer koje je ubio okrutni serijski ubojica poznat kao „Crveni John" a koji će se na njegovom putu naći i u budućnosti.