Scarlett Marquesa zostaje otruta podczas przyjęcia organizowanego przez siebie. Agenci przesłuchują gości oraz członkinie klubu sportowego, któremu przewodniczyła zmarła. Okazuje się, że elity skrywają wiele tajemnic.
When the CBI investigates the kidnapping of a prominent lawyer and state house lobbyist, the CBI Director wants Jane on the case, but he is uncertain of his future with the unit after his encounter with Red John.
Patrick jest zmuszony po raz kolejny stawić czoła Bretowi Stilesowi, założycielowi sekty Visualize. Od niego właśnie Jane dowiaduje się cennych szczegółów o Czerwonym Johnie i porwanej przez niego psycholog Kristinie Frye.
When Dr. Alicia Seberg, a government research scientist, is exposed to a deadly toxin while at work and has only hours to live, she calls Patrick Jane and the CBI to find her murderer.
Patrick and the CBI team investigate the murder of a tutor, and find a mysterious little red box near the body, starting a chain of events that turns the murder into the search for a priceless ring stolen from the British Museum. Meanwhile, Lisbon is worried when a new boss, Madeleine Hightower, takes command of the CBI, as well as mysteriously learning about Rigsby and Van Pelt's relationship.
When a "Jane Doe" with amnesia and covered in blood steps in front of Cho and Van Pelt's car, Patrick Jane must use all of his skills to discover who she is, her last location and why she lost her memory
When Patrick Jane's sneaky conduct causes the case of a confessed hitman to be tossed out of court, his annoyed CBI team must start the investigation over from scratch.
When a media mogul is murdered, Patrick Jane and the CBI team investigate cult leader Bret Stiles, who may have had an axe to grind following the publication of a critical story about his group.
Romantic sparks begin to fly when Patrick Jane and supposed psychic Kristina Frye cross paths again during the CBI investigation into the murder of a charismatic head of a non-profit organization that fights human trafficking.
Patrick Jane and Kristina's first date is interrupted by a report of Red John striking again, which is discovered to be a copycat. But when Kristina reaches out to the real Red John, both she and Jane find themselves in grave danger.
Pomoću jedinstvenog dara moderni Sherlock Holmes uvijek je korak ispred forenzičkih analiza, napredne kriminalističke tehnologije i svih kolega. Uočavajući najsitnije detalje, igrajući umne igrice i „čitajući" emocije drugih, Jane kriminalcima kompleksnih profila i poremećenih umova postavlja sofisticirane umne zamke te može navesti svjedoke i osumnjičene da mu razotkriju činjenice kojih ni sami nisu svjesni. Šarmantni i karizmatični Jane ima neslavnu prošlost televizijskog vidovnjaka te je stekao negativni publicitet nakon što je razotkriven kao varalica. Iako je priznao kako nema paranormalne, već samo mentalne sposobnosti, jedina koja i dalje sumnja u njega je narednica CBI-a Teresa Lisbon (Robin Tunney). Iako je nepredvidljiv i poznat po zaobilaženju protokola, njegovi kolege, agenti Kendall Cho (Tim Kang) i Wayne Rigsby (Owain Yeoman) te novakinja Grace Van Pelt (Amanda Righetti), dive se njegovom šarmu i učinkovitosti u rješavanju slučajeva. No Jane skriva još jednu mračnu tajnu iz svoje prošlosti. Naime, nekoliko godina prije početka same radnje Jane je izgubio suprugu i kćer koje je ubio okrutni serijski ubojica poznat kao „Crveni John" a koji će se na njegovom putu naći i u budućnosti.